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dan he xi bao - xue xiao ban ju ji wu ce ding zai xin nao xue guan xue zuo zheng zhen duan zhong de yi yi
Author(s): 
Pages: 649-650
Year: Issue:  6
Journal: Research of Traditional Chinese Medicine

Keyword:  血瘀证单核细胞-血小板聚集物血小板活化心脑血管病;
Abstract: 目的通过比较单核细胞-血小板聚集物(MPA)在正常人与心脑血管血瘀证病人中的表达,探讨MPA与血瘀证之间的相关性。方法选取84例心脑血管血瘀证病人,包括急性血瘀证组11例(急性心肌梗死,急性脑梗死),慢性血瘀证组65例(症状相对平稳的冠心病、脑梗死)和轻型血瘀证组8例(高血压,短暂性脑缺血发作);另随机选取30名正常人作为正常组。采用流式细胞仪检测CD14、CD41,从而得出MPA表达的百分率数值。结果血瘀证各组与正常组比较MPA数值均增加(P<0.01),急性血瘀证组>慢性血瘀证组>轻型血瘀证组>正常组。MPA数值与血瘀证积分呈直线正相关关系(r=0.93,P<0.05)。结论MPA测定在血瘀证诊断中有着重要的意义,并对判断血瘀证轻重、预测心脑血管疾病的发生有一定的价值。
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