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chen jiu xing xin ji geng si da shu mo xing de zhi bei
Author(s): 
Pages: 365-366
Year: Issue:  3
Journal: Research of Traditional Chinese Medicine

Abstract: 1方法Wistar大鼠101只,10%水合氯醛腹腔注射麻醉,以肢体导联(Ⅱ导联)进行心电图监测。气管切开插管接动物呼吸机,在胸骨左缘心脏搏动处切口,经第3肋与第4肋间分离开胸暴露心脏,在左心耳下缘与肺动脉圆椎间距主动脉根部约3mm处进针,结扎左冠状动脉前降支,以心电图出现ST段弓背向上抬高大于0.2mV,持续30min以上作为模型成功的标志[1]。术后肌肉注射青霉素80×104U,连用7d,预防感染。3周后观察大鼠存活情况,复查心电图并开胸观察心肌组织的形态学变化。2结果2.1心电图变化术中结扎左冠状动脉前降支后,心电图出现ST段弓背向上抬高(大于0.2mV),其中,ST段在10s内抬高的有5
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