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Effect of Zhongfengkang on Cerebral Glutamate and Calcium of Rats with Focal Cerebral Ischemia
Pages: 877-878
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  Zhongfengkangcerebral ischemiaglutamateoverload of calcium;
Abstract: Objective To observe the effect of Zhongfengkang on content of glutamate and calcium in focal cerebral ischemia in rats.Methods The models of focal cerebral ischemia were made by inserting nylon thread. The content of glutamate and calcium in focal cerebral ischemia rats were observed in 3h after cerebral ischemia.Results Compared with sham operation group, the content of glutamate and calcium increased in model group(P<0.01).The content of glutamate and calcium decreased in the treatment groups(P<0.05 or P<0.01).Conclusion By reducing content of glutamate and calcium, Zhongfengkang could reduce excitotoxicity and overload of calcium,and reduce damage of cerebral ischemia effectively.
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