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Effects of Ketamine Preconditioning on the Microvascular Endothelial Cell, Tumor Necrosis Factor-α and Nuclear Factor kappa β in Rabbits with Lung Ischemia Reperfusion Injury
Author(s): XI Jian-hua, LIN Li-na
Pages: 10-
14
Year: 2009
Issue:
8
Journal: Zhejiang Journal of Preventive Medicine
Abstract: 目的 探讨氯胺酮预处理对兔肺缺血再灌注损伤中微血管内皮细胞、核因子-κβ和肿瘤坏死因子-α的影响.方法 采用改良Sekido法制备免肺缺血再灌注损伤(Lung Ischemia-Reperfusion Injury LIRI)模型,随机分为假手术组(C组)、缺血再灌注损伤组(IR组)、氯胺酮预处理(KET组).观察氯胺酮对兔肺缺血再灌注损伤的保护作用及其机制.结果 KET组与IR组相应时间点相比核...
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