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plastic surgery
Pages: 59-64
Year: Issue:  2
Journal: China Medical Abstracts

Abstract: 209277 Experimental study of PVPP/silicone composite automatic expanded material as implansts/Yin Weimin(Dept Plast Surg,Nanfang Hosp,Southern Med Univ,Guangzhou 510000)…∥Chin J Plast Surg.-2009,25(2).-140145Objective To study the feasibility of Polyvinylpolypyrrolidone(PVPP)/silicone composite automatic expanded material as impants.Methods The PVPP hydrogel was mixed with silicone through the thiolocation at the high temperature.Implants with different ratio of PVPP to silicone were placed under the back and nose skin in 24 New Zealand rabbits.The surrounding tissue reaction,material and skin expansion were observed and compared with those with pure silicone implants.Results The study lasted for 200 days.Compared with pure silicone implants,the composite material could expand automatically and stop expanding at about 2weeks after implantation.Histological study showed similar infectional and foreign body reaction around the composite material and the pure silicone.Conclusion Compared with pure silicone,the PVPP/silicone composite implant has the advantage of automatic expansion,so as to expand the soft tissue.16 refs,5 figs,1 tab.
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