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infection
Pages: 5-6
Year: Issue:  2
Journal: China Medical Abstracts

Abstract: 209159 Pseudomonas aeruginosa nosocomial infections after open heart surgery:a clinical analysis/Zhou Ye(Beijing Anzhen Hosp Affil Cap Univ Med Sci,Beijing 100029)…∥Chin J Nosocomiol.-2009,19(6).-677679Objective To investigate the clinical distribution and antibiotics resistance of Pseudomonas aeruginosa nosocomial infection after open-heart operation.Methods The clinical data of 393 patients with nosocomial infection from Jan 2004 to Dec 2007 were analyzed retrospectively.Results There were 57 infected cases caused by P. aeruginosa,and accounted for 14.5% of all infections during the period.All infected patients had serious original heart diseases,and received broad-spectrum antibiotic therapy preciously.Forty-two patients developed postoperative cardiorespiratory function failure,and 28 patients needed circulatory support.Thirty-six patients prolonged mechanical ventilation time for over 1 week.Results of susceptibility test showed that ciprofloxacin,levofloxacin and piperacillin/tazobactam were the most active antibiotics,followed by tobraycin,netilmicin,getamicin,meropenem and imipenem/cilastatin. P. aeruginosa presented high resistance to ceftazidime and cefoperazone/sulbactam.
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