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chan chao guang pu - nei zuo an mei fei yan ke lei bo jun de nai yao xing fen xi
Author(s): 
Pages: 554,570
Year: Issue:  5
Journal: Experimental and Laboratory Medicine

Abstract:  目前抗菌药物在临床上的大量使用,甚至是滥用导致细菌的耐药性问题引起了有关部门的高度关注,卫生部也出台了临床抗菌药物分级管理规范,超广谱β-内酰胺酶(ESBLs)是造成革兰阴性杆菌对β-内酰胺类抗菌药物耐药的重要原因之一,在临床实际检测中,发现肺炎克雷伯菌是重要致病菌之一,也是重要医院感染病原菌之一[1,3],此类菌株具有较高的交叉耐药性和多重耐药性,导致患者住院时间延长、费用增加、死亡率增高.
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