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Experimental study on pioglitazone inducing PC-3 cells apoptosis
Author(s): ZHU Shaoxing, CHEN Liu, WANG Bin
Pages: 404-
407
Year: 2008
Issue:
5
Journal: Journal of Fujian Medical University
Abstract: 目的 研究吡格列酮对前列腺癌(Pca)PC-3细胞凋亡的诱导作用及其可能机制.方法 体外培养Pca PC-3细胞,以不同浓度(0,0.1,1,10,100 μmol/L)的吡格列酮干预细胞,四氮唑蓝比色法(MTT)和原位细胞凋亡检测法(Tunnel)检验吡格列酮对Pca PC-3细胞的增殖抑制及诱导凋亡作用,流式细胞术检测其对Caspase-3表达的影响.结果 10,100 μmol/L吡格列酮对...
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