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Association of ENA-78,IP-10 and VEGF gene polymorphism with idiopathic pulmonary fibrosis
Pages: 2690-2694
Year: Issue:  38
Journal: National Medical Journal of China

Keyword:  Pulmonary fibrosisChemokine CXCL5Chemokine CXCL10Vascular endothelial growth factorsPolymorphismsingle nucleotide;
Abstract: 目的 探讨上皮中性粒细胞活化肽78(ENA-78)、干扰素诱导蛋白10(IP-10)和血管内皮生长因子(VEGF)的基因多态性与特发性肺纤维化(IPF)的相关性.方法 采用聚合酶链反应-限制片段长度多态性技术,检测60例住院IPF患者(IPF组)和60例年龄、性别、吸烟情况匹配的外伤、骨折住院患者(对照组)的ENA-78(-156G/C)、IP-10(-1596C/T)和VEGF(+405G/C)...
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