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mei du xue qing gu ding mian yi xue yan jiu jin zhan
Author(s): 
Pages: 689-691
Year: Issue:  9
Journal: China journal of Leprosy and Skin Diseases

Keyword:  血清固定梅毒免疫;
Abstract: 梅毒血清固定是指梅毒患者经规范驱梅治疗后临床表现消失,早期梅毒6个月,晚期梅毒12个月,其血清反应素试验不转阴或血清反应素抗体滴度固定在某个水平不转阴持续3个月.其病因与发病机制不明,可能系多因素综合作用的结果.多认为机体免疫系统抑制及紊乱是其发生的主要机制.最近研究表明血清固定还可能与梅毒螺旋体的基因改变有关,机体Toll样受体及树突状细胞的功能状态也与其有关.
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