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Analysis of Factors Related with Gastric pH Value in Patients with Chronic Gastritis
Author(s): 
Pages: 491-492
Year: Issue:  8
Journal: Chinese Journal of Gastroenterology

Keyword:  胃酸胃炎萎缩性糖尿病螺杆菌幽门;
Abstract: 背景:传统观点认为胃酸分泌随年龄增加和胃黏膜萎缩而减少,但也有研究持不同观点.目的:研究慢性胃炎患者胃内pH值与性别、年龄、糖尿病、萎缩和幽门螺杆菌(H. pylori)感染之间的相关性.方法:共纳入67例慢性胃炎患者.采用pH试纸测定胃液pH值,病理切片结合快速尿素酶试验或13C-尿素呼气试验检测H. pylori感染情况.分析不同因素与慢性胃炎患者胃内pH值的相关性.结果:67例患者中,慢性非萎缩性胃炎患者35例(52.2%),慢性萎缩性胃炎32例(47.8%);H. pylori阳性21例(31.3%),H. priori阴性46例(68.7%).平均胃内pH值为2.86.胃内pH值随年龄增长呈升高的趋势(P=0.15).Logistic回归分析显示胃内pH值与性别(P=0.17)、年龄(P=0.06)、糖尿病(P=0.75)、萎缩(P=0.67)和H. priori感染(P=0.11)均无相关性.结论:性别、年龄、糖尿病、萎缩和H. pylori感染不是影响慢性胃炎患者胃内pH值的重要因素.
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