The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Relationship between expression of Kiss-1 and nm23 and lymph node metastasis in breast cancer
Author(s): 
Pages: 171-174
Year: Issue:  3
Journal: China Oncology

Keyword:  Kiss-1nm23乳腺肿瘤转移淋巴结;
Abstract: 背景与目的:Kiss-1和nm23是肿瘤转移抑制基因,其蛋白表达与乳腺癌的转移密切相关.本研究探讨Kiss-1及nm23蛋白在乳腺癌中的表达与腋窝淋巴结转移的关系.方法:用免疫组化技术检测70例乳腺癌中Kiss-1及nm23蛋白表达.结果:乳腺癌中Kiss-1与nm23蛋白的阳性表达率分别为62.86%和68.57%,其中有淋巴结转移者的阳性表达率分别为38.46%和50.00%,明显低于无淋巴结转移者的阳性表达率77.27%和79.55%(P(0.05).Kiss-1与nm23蛋白表达均阳性患者的淋巴结转移率(14.29%)明显低于其他患者(P<0.05). 结论:Kiss-1与nm23具有抑制乳腺癌淋巴结转移的作用,可能成为预测乳腺癌淋巴结有无转移的生物学标志.
Related Articles
No related articles found