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tuo pu ti kang lian he shun bo zhi liao xiao xi bao fei ai 46 li liao xiao guan cha
Author(s): 
Pages: 87-88
Year: Issue:  2
Journal: China Modern Doctor

Keyword:  拓扑替康小细胞肺癌;
Abstract: 目的 观察拓扑替康联合顺铂治疗23例小组胞肺癌的临床疗效和毒副作用.方法 TPT 1.2mg/m2,静滴d1-5,PDD 30mg/m2,静滴d1-3;同时予以止吐治疗.21d为一周期,连用2周期评价疗效.结果 46例患者中CR 6例;PR 21例,有效率58.7%.其中初治病人毒副反应主要以血清毒性反应为主,一般7~10d出现,骨髓抑制Ⅳ度1例、Ⅲ度5例、Ⅱ度9例、Ⅰ度17例.胃肠道反应Ⅲ度2例、Ⅱ度5例、Ⅰ度9例.脱发8例.结论 TPT联合PDD治疗SCLC疗效确切,其毒副反应相对轻微,患者易于耐受,化疗结束后即可恢复,该方案值得进一步研究.
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