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The Significance of the hsCRP and BNP in Patients with Coronary Heart Disease after Coronary Intervention
Author(s): 
Pages: 14-15
Year: Issue:  2
Journal: China Modern Doctor

Keyword:  血浆超敏C反应蛋白脑钠肽经皮冠状动脉支架置入冠状动脉造影;
Abstract: 目的 探讨血浆超敏C反应蛋白(hsCRP)、脑钠肽(BNP)在冠心病诊治中的价值.方法 测定并比较40例急性心肌梗死(AMI)或不稳定性心绞痛(UAP)组、30例稳定性心绞痛(SAP)组和冠状动脉造影正常对照组(NOR)的血浆hsCRP、BNP的差异,观察冠心病患者经皮冠状动脉支架置入(PCI)3d、3个月及NOR组造影术后上述指标的变化.结果 hsCRP在AMI/UAP组显著高于SAP/NOR组(P<0.05),而SAP组与NOR组无差异(P>0.05),PCI术后3d,hsCRP明显升高而BNP下降,术后3个月BNP和hsCRP均明显下降(P<0.05).BNP在冠心病组高于对照组(P<0.05),PCI术后BNP下降.NOR组冠状动脉造影术后hsCRP和BNP均无明显变化.结论 hsCRP是反映冠状动脉粥样斑块稳定性的一个指标,BNP能反映冠心病患者心功能的恢复.
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