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di sai mi song yu fang fu ke shu hou ma fei zhen tong bu liang fan ying de lin chuang guan cha
Author(s): 
Pages: 280-281
Year: Issue:  2
Journal: The Journal of Practical Medicine

Keyword:  镇痛地塞米松吗啡不良反应;
Abstract: 目的:观察地塞米松预防妇科术后硬膜外吗啡镇痛的效果.方法:将80例ASA Ⅰ~Ⅱ级经腹行妇科手术后镇痛的患者分为两组,每组40例,实验组首量硬膜外腔注射吗啡2 mg+地塞米松3 mg+生理盐水共5mL,维持用0.125%布比卡因+吗啡6 mg+地塞米松5 mg+生理盐水共100 mL.对照组首量吗啡2 mg+生理盐水共5 mL,维持用0.125%布比卡因+吗啡6 mg+生理盐水共100 mL.两组均使用同一品牌一次性镇痛泵,背景输注均为2 mL/h,记录镇痛过程中恶心、呕吐、皮肤瘙痒等副作用的状况.结果:实验组恶心1例,无呕吐、皮肤瘙痒等,对照组恶心10例,呕吐5例,皮肤瘙痒5例.实验组恶心、呕吐、皮肤瘙痒等副作用发生率明显低于对照组,差异有显著性(P<0.01).结论:地塞米松对预防妇科术后吗啡镇痛不良反应有明显效果.
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