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Application of v-interferon secretory reaction in peripheral blood monocytes in diagnosis of tuberculosis in patients with immunosuppression
Author(s): 
Pages: 207-209
Year: Issue:  2
Journal: The Journal of Practical Medicine

Keyword:  结核干扰素Ⅱ型诊断免疫抑制;
Abstract: 目的:探讨体外单核细胞γ干扰素(IFN-γ)分泌反应对免疫抑制患者肺结核诊断的临床意义.方法:应用ELISPOT的方法检测了12名健康体检者(健康对照组)、12名结核病患者(结核病对照组)和12名免疫抑制合并结核病患者(免疫抑制合并结核病组)体外单核细胞IFN-γ分泌反应.结果:健康对照组中除1人有结核病接触史者,IFN-γ分泌反应呈阳性外,其余均为阴性:结核病对照组中除1名患者痰培养证实为非结核分枝杆菌,其IFN-γ分泌反应呈阴性外,其余均为阳性;免疫抑制合并结核病患者均为阳性.结论:体外单核细胞IFN-γ分泌反应有助于临床对免疫抑制患者合并肺结核的诊断.
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