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ren gong guan jie zhi huan shu hou shen jing mai xue shuan xing cheng de ji yin duo tai xing yan jiu jin zhan
Author(s): 
Pages: 871-873
Year: Issue:  11
Journal: Chinese Journal of Surgery

Abstract: 人工全髋关节置换术(total hip arthroplasty,THA)和全膝关节置换术(total knee arthroplasty,TKA)由于手术创伤、止血带使用、骨水泥使用、长时间卧床等因素的影响,术后深静脉血栓(deep vein thrombosis,DVT)发生率较高,尤其是TKA术后DVT的发生率更高.国内报道一组人工关节置换术后DVT发生率为47.1% [1](TKA为53.8%,THA为40.0%).DVT是一种环境与遗传共同作用的多因素疾病,其形成原因是血液淤滞,血管壁异常和血液性质的改变 [2].目前关于基因缺陷导致DVT的分子遗传学研究已经比较深入,本文就国内外THA、TKA术后DVT形成的分子遗传学研究进展作一综述.……
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