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The expression of C-erbB-2 in breast invasive ductal carcinoma
Author(s): 
Pages: 1307-1308
Year: Issue:  11
Journal: Hebei Medical Journal

Keyword:  乳腺浸润性导管癌免疫组织化学C-erbB-2癌基因;
Abstract: 目的 探讨C- erbB-2在乳腺癌中的表达意义.方法 采用免疫组化SP法检测161例乳腺浸润性导管癌中C-erbB-2的表达.结果 C-erbB-2在<50岁与≥50岁年龄组表达率分别为27.43%和31.25%,差异无统计学意义(P>0.05);在浸润性导管癌Ⅰ、Ⅱ、Ⅲ级中表达率分别为19.05%、24.21%、42.22%,在Ⅰ、Ⅱ级中明显低于Ⅲ级中(P<0.05);在淋巴结无转移组、低转移组表达率分别为20.43%、29.41%,明显低于高转移组44.0%(P<0.05).结论 C-erbB-2的表达与乳腺癌的组织学分级高,淋巴结高转移率密切相关.C-erbB-2的检测可作为乳腺癌预后判断的重要参考指标.
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