Author(s): DUAN Xiang-qing, OUYANG Xiang-ying, HU Rong
Pages: 351-354
Year: 2009 Issue:  6
Journal: Chinese Journal of Stomatology
Keyword:  Periodontitis; Coronary disease; C-reactive protein; Initial periodontal therapy;
Abstract: Objective To investigate the clinical results of initial periodontal therapy on chronic periodontitis patients with stable coronary heart disease. Methods Thirty-two chronic periodontitis patients with stable coronary heart disease were included in this prospective study. All subjects received oral hygiene instruction, scaling and root planing and clinically monitored for 3 months. The clinical parameters,including plaque index(PLI) , probing depth (PD) , attachment loss(AL) and bleeding index(BI) , were recorded at baseline and 3 months after treatment. Serum levels of high-sensitivity C-reactive protein (hs-CRP) , cholesterol (CHO) , triglyceride (TG) , high-density lipoprotein (HDL) , low-density lipoprotein(LDL) and glucose (GLU) were also measured. Results At 3 months after initial periodontal therapy, the mean PD of patients reduced from(3.95±0.15)mm to(2.93±0.21)mm(P＜0.01),the mean AL from(3.08±0.43)mm to(2.43±0.37)mm(P＜0.01),the percentage of sites with PD≥5 mm from (22.37±6.88)%to(3.00±1.80)%(P＜0.01).hs-CRP significantly decreased at 3 months after treatment compared with baseline[(2.71±2.69)mg/L vs.(1.99±2.14)mg/L,P＜0.05].CHO,TG,HDL,LDL and GLU decreased slightly(P＞0.05).Conclusions Initial periodontal therapy is effective for chronic periodontitis patients with stable coronary heart disease.After initial periodontal therapy,periodontal parameters improved significantly and serum levels of hs-CRP decreased.