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Exploration on the decreased expression of adhesion molecules in blood plasma of cerebral infraction patients by naloxone
Author(s): 
Pages: 59-60
Year: Issue:  9
Journal: CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES

Keyword:  纳洛酮脑梗死黏附分子;
Abstract: 目的 探讨纳洛酮(naloxone)降低血浆中黏附分子sICAM-1、VCAM-1的表达.方法 应用酶联免疫吸附法测定15例脑梗死患者急性期和恢复期血浆中sICAM-1、VCAM-1含量,并与12例对照组患者血浆中sICAM-1、VCAM-1含量作对照观察.结果 对照组有较高的黏附分子表达水平,纳洛酮治疗组黏附分子表达水平显著低于对照组(P<0.05).结论 纳洛酮可能通过减轻脑梗死后局部的炎性反应,从而起到脑保护作用.
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