Antioxidant Activity In Vitro of Three Constituents from Caesalpinia sappan L
Author(s): HU Jun, YAN Xiaoling, WANG Wei, WU Hao, HUA Lei, DU Lijun
Pages: 474-479
Year: 2008 Issue: 4
Journal: TSINGHUA SCIENCE AND TECHNOLOGY
Keyword: antioxidant; Caesalpinia sappan L; protosappanin A; protosappanin B; brazilein;
Abstract: Antioxidant activities of the 95% ethanol extract from Caesalpinia sappan heartwood (ECS),pro-tosappanin A,protosappanin B,and brazilein were studied in vitro.The inhibition of the formation of malondialdehyde (MDA) and the scavenging of superoxide anions,hydrogen peroxide,and hydroxyl radicals were assayed.The experimental results show that all four substances had antioxidant activity in vitro but their capabilities differed for the different indicators.ECS,protosappanin A,and protosappanin B show more inhi-bition of MDA and scavenging of hydrogen peroxide,while brazilein shows more scavenging of hydroxyl radicals.All the samples show little scavenging of superoxide anions.
Pages: 474-479
Year: 2008 Issue: 4
Journal: TSINGHUA SCIENCE AND TECHNOLOGY
Keyword: antioxidant; Caesalpinia sappan L; protosappanin A; protosappanin B; brazilein;
Abstract: Antioxidant activities of the 95% ethanol extract from Caesalpinia sappan heartwood (ECS),pro-tosappanin A,protosappanin B,and brazilein were studied in vitro.The inhibition of the formation of malondialdehyde (MDA) and the scavenging of superoxide anions,hydrogen peroxide,and hydroxyl radicals were assayed.The experimental results show that all four substances had antioxidant activity in vitro but their capabilities differed for the different indicators.ECS,protosappanin A,and protosappanin B show more inhi-bition of MDA and scavenging of hydrogen peroxide,while brazilein shows more scavenging of hydroxyl radicals.All the samples show little scavenging of superoxide anions.
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