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Experimental study on the antidepressant effects of Xuancaohua
Author(s): 
Pages: 682-683
Year: Issue:  8
Journal: NINGXIA MEDICAL JOURNAL

Keyword:  萱草花强迫游泳悬尾实验利血平抗抑郁;
Abstract: 目的 观察萱草花对小鼠抑郁模型的抗抑郁作用.方法 将小鼠分为5组,即阴性对照组、阳性药物组和萱草花水煎剂组(按不同剂量分3组),行小鼠强迫游泳、小鼠悬尾和拮抗利血平所致的抑郁症状实验.结果 萱草花高、中剂量组(6.000、3.000s/kg)均可显著缩短小鼠强迫游泳、悬尾不动时间、拮抗利血平所致小鼠运动不能作用(P<0.01)和小鼠眼睑下垂作用(P<0.05).萱草花高、中、低剂量(1.500g/kg)组拮抗利血平所致小鼠体温下降作用(P<0.01).结论 萱草花对小鼠抑郁症的强迫游泳模型、悬尾模型和拮抗利血平所致的抑郁症模型均有显著治疗作用,且作用与药物的剂量密切相关.
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