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Author:
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Year:
Volume:
Issue:
fu pian kou fu ye de yao xiao xue yan jiu
Author(s):
LI Te
,
SHU Ke
,
LI Ying
,
SHU Zuo
Pages:
44
-
45
Year:
2008
Issue:
6
Journal:
YUNNAN JOURNAL OF TRADITIONAL CHINESE MEDICINE AND MATERIA MEDICA
Keyword:
附片口服液
;
药效学
;
急性失血性休克
;
急性心功能不全
;
垂体-肾上腺皮质功能
;
Abstract:
目的:对中药制剂附片口服液进行药理学研究,为其临床应用提供理论依据.方法:用麻醉大鼠经颈动脉放血造成动物急性失血性休克模型;经腹部静脉恒速输注普萘诺尔和维拉帕米混合液,造成大鼠急性心功能不全模型.观察经十二指肠给予不同剂量的附片液后对上述2种动物模型的影响.此外,还观察了附片液对垂体-肾上腺皮质功能的影响.结果及结论:附片液有明显抗急性失血性休克和缓解化学物质所致急性心功能不全的作用,同时还具有兴奋垂体-肾上腺皮质轴,提高肾上腺皮质功能的作用.
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