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Clinical significance of changes in peripheral blood lymphocyte subsets in patients with lung cancer
Author(s): 
Pages: 452-454
Year: Issue:  7
Journal: ACTA ACADEMIAE MEDICINAE XUZHOU

Keyword:  肺肿瘤淋巴细胞免疫分型免疫监测;
Abstract: 目的 探讨肺癌患者外周血淋巴细胞免疫分型,了解肺癌患者的基线免疫状态.方法 采用流式细胞仪分别检测60例肺癌患者(肺癌组)和20例正常人(对照组)外周血淋巴细胞免疫分型,并对两组进行比较.结果 肺癌患者CD3(+)、CIM(+)、自然杀伤细胞(NK细胞)比例及CD4(+)/CD8(+)比值均低于对照组(P<0.05),CD8(+)细胞比例高于对照组(P<0.05),CD19(+)细胞比例与对照组相比差异无显著性(P>0.05).结论 肺癌患者免疫功能与正常人群相比存在降低趋势,外周血淋巴细胞免疫分型可作为肺癌患者免疫监测的一种方法.
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