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Endoscopic splender dilation combined with photodynamic therapy and local chemotherapy for treatment of esophagocadial cancer stenosis
Author(s): 
Pages: 454-457
Year: Issue:  7
Journal: ACTA ACADEMIAE MEDICINAE XUZHOU

Keyword:  光动力疗法局部化疗探条扩张食管贲门癌癌性狭窄;
Abstract: 目的 评价经内镜探条扩张术联合光动力疗法(PDT)及局部化疗治疗食管贲门癌性狭窄的临床疗效.方法 食管贲门癌患者91例,按治疗方法分为对照组(PDT联合局部化疗)和联合扩张治疗组(经内镜探条扩张联合PDT及局部化疗).所有病例以3~5 mg/kg剂量的血啉甲醚静脉滴注,用药后3 h内于肿瘤病变处注射化疗药物(5-Fu)并激光照射.联合扩张治疗组41例在以上治疗前3天内进行经内镜探条扩张治疗.结果 联合扩张治疗组吞咽困难缓解率显著高于对照组.近期疗效及平均生存期2组间无显著差异.结论 经内镜扩张术联合PDT及局部化疗可显著改善食管贲门癌性狭窄临床症状.
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