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gan ying hua huan zhe ning xue wu xiang de jie guo fen xi
Author(s): 
Pages: 60-61
Year: Issue:  5
Journal: WORLD HEALTH DIGEST·MEDICAL MONTHLY

Keyword:  肝硬化凝血酶原时间活化部分凝血活酶时间;
Abstract: 目的分析肝硬化患者血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)、抗凝血酶Ⅲ(AT Ⅲ)的变化.方法采用全自动血凝仪测定100例健康人和92例肝硬化患者的血浆PT、APTT、FIB、TT、AT.结果肝硬化患者与对照组比较PT、APTT、TT均延长(P<0.01),FIB显著减少(P<0.01),AT Ⅲ活性明显降低(P<0.01).结论肝硬化患者存在明显的凝血、抗凝血、纤溶指标异常,且与肝硬化程度密切相关.通过对肝硬化患者凝血五项功能的监测,为临床防治肝硬化患者出血、判断预后和降低病死率提供理论依据.
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