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shu fen tai ni yong yu fang zhi rui fen tai ni fu he ma zui shu hou ji xing teng tong
Author(s): 
Pages: 31-33
Year: Issue:  18
Journal: CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE

Keyword:  舒芬太尼瑞芬太尼急性疼痛;
Abstract: 目的 评估舒芬太尼在减轻以瑞芬太尼进行静吸复合全身麻醉后急性疼痛的临床疗效.方法 60例择期行腹腔镜下胆囊切除术的患者,随机分为舒芬太尼组(SF组)、芬太尼组(F组)和曲马多组(T组),每组各20例.手术结束前10min,SF组静脉注射舒芬太尼0.15μg/kg, F组静脉注射芬太尼1.5μg/kg, T组静脉注射曲马多1.5mt/kg.记录并比较三组苏醒后的视觉模拟评分(VAS)、镇静评分、舒适评分和不良反应发生例数.结果 SF组患者拔管后10、30、60min的VAS分别为(1.38±1.74)分、(1.28±1.01)分、(1.15±1.10)分,较F、T组低(P<0.05);SF组各时间点的舒适评分、镇静评分较F、T组高(P<0.05);T组恶心、呕吐的发生率(35.0%、25.0%)高于SF、F组(P<0.05);F组呼吸抑制的发生率(25.0%)高于SF、T组(P<0.05).结论 舒芬太尼在控制瑞芬太尼麻醉术后急性镇痛中的效果较芬太尼、曲马多更佳,具有不良反应少、舒适度高的优点.
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