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Epidemiological investigation of brucellar spondylitis and relative clinical study on its therapy
Author(s): 
Pages: 1632-1634
Year: Issue:  9
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  布鲁杆菌病椎关节炎流行病学疗程药物配伍;
Abstract: 目的:总结布氏杆菌性脊椎炎流行病学特点及最佳药物治疗方案,为提高对该病的药物选择及治疗效果提供科学依据.方法:采集113例确诊患者临床流行病学资料,采用5种不同药物,分成5组不同配伍方法,进行不同疗程治疗和对比研究.结果:布氏杆菌性脊椎炎女性发病率高,平均年龄41岁,坝上发病率高于坝下,主要集中在饲养、放牧牲畜而受染,病灶分布多在腰椎,2个椎体受累最多,涉及L4的发病率最高并破坏最为明显;含强力霉素治疗组效果优于未含强力霉素组,差异有显著性(P<0.05),如增加疗程,疗效增加不明显.结论:布氏杆菌性脊椎炎临床流行病学具有特征性;以强力霉素+庆大霉素+磺胺甲基异噁唑为首选的抗菌素,应用两个疗程是治疗和防止本病复发最合理的方法.
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