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Experimental study of hyaluronate and prednisolone on indirect temporomandibular joint trauma
Author(s): 
Pages: 296-299
Year: Issue:  3
Journal: JOURNAL OF MODERN STOMATOLOGY

Keyword:  动物模型颞下颌关节透明质酸泼尼松龙间接性损伤;
Abstract: 目的 探讨透明质酸和泼尼松龙对间接性颞下颌关节损伤的治疗作用.方法 选用新西兰白兔36只,分为3个实验组:透明质酸治疗组、泼尼松龙治疗组、损伤对照组和1个正常对照组.切除标本通过光镜,扫描电镜,组织化学方法观察.结果 损伤后3天泼尼松龙组显示对损伤反应明显的抑制作用,7天、30天、90天时,HA组促进损伤修复的作用显著,髁突前斜面增殖带PCNA阳性细胞计数较泼尼松龙组多(P<0.01).结论 HA在TMJ损伤早期对损伤的抑制作用小于泼尼松龙.HA对促进TMJ间接性损伤后的修复作用优于泼尼松龙.
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