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Clinical Study on the Treatment of Primary Liver Cancer by Cinobufotain Combined with Transcatheter Arterial Chemoembolization
Author(s): 
Pages: 32-34
Year: Issue:  2
Journal: ACTA UNIVERSITATIS TRADITIONIS MEDICALIS SINENSIS PHARMACOLOGIAEQUE SHANGHAI

Keyword:  肝肿瘤华蟾素化疗栓塞介入疗法;
Abstract: 目的:探讨中药华蟾素联合肝动脉介入化疗栓塞(TACE)对原发性肝癌的治疗作用.方法:96例肝癌住院患者随机分为两组.治疗组50例,采用华蟾素静脉滴注联合TACE;对照组46例,采用单纯TACE治疗.治疗后1周测定两组白细胞、肝功能变化;4周后分别测定生活质量、瘤体体积,并观察两组生存期.结果:治疗组在抑制肿瘤生长方面与对照组无差异,对生活质量的改善明显优于对照组(P<0.05);两组0.5年生存率无明显差别(P>0.05),1~2年生存率治疗组明显高于对照组(P<0.05).治疗组治疗后外周血WBC、CD3+、CD4+、CD4/CD8、NK均高于对照组,而血清总胆红素(TBil)、血清丙氨酸氰基转移酶(ALT)均低于对照组(P<0.05).结论:华蟾素能够提高TACE患者的疗效,改善免疫功能,并能降低毒副反应.
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