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liu shi xi bao shu jian ce man xing zai sheng zhang ai xing pin xue huan zhe wai zhou xue t lin ba xi bao ya qun de bian hua ji lin chuang yi yi
Author(s): 
Pages: 83-84
Year: Issue:  z2
Journal: CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE

Keyword:  再生障碍性贫血T淋巴细胞亚群流式细胞术;
Abstract: 目的 观察慢性再生障碍性贫血(CAA)患者外周血T淋巴细胞(CD3)及其亚群(CD4,CD8)和比值(CD4/CD8)的变化,探讨机体免疫功能和CAA发病的关系.方法 采用流式细胞仪对37例CAA患者(CCA组)和30例健康人(对照组)外周血CD3及CD4,CD8进行检测.结果 与对照组相比,CCA组CD3无明显变化(P>0.05),CD4、CD4/CD8显著降低(P<0.01).而CD8水平则显著升高(p<0.01).结论 CAA患者存在细胞免疫异常,以T淋巴细胞亚群失调为特征,与CAA的发病有密切关系.
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