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ren shen qi da shu zheng ji ya yi dong guo cheng zhong ya zhou zu zhi nei tgf- 1 de biao da
Author(s): 
Pages: 85-86
Year: Issue:  1
Journal: HEILONGJIANG MEDICINE AND PHARMACY

Keyword:  转化生长因子β1孕鼠牙周组织;
Abstract: 目的:观察妊娠期大鼠正畸牙移动过程中转化生长因子β1(TGF-β1)在大鼠牙周组织中的表达,探讨TGF-β1与正畸牙齿移动的关系.方法:将未孕组大鼠和受孕第1天的妊娠组大鼠在上切牙与磨牙间安放正畸装置,分别于加力后4、8、12、16d分批处死,取材进行HE和免疫组化染色.结果:大鼠牙移动过程中,妊娠组牙周组织TGF-β1表达强于未孕组.而加力4d组和8d组张力侧TGF-β1表达明显增多,大于压力侧.结论:TGF-β1与孕鼠牙移动过程中牙周组织的改建密切相关,并且有促进成骨的作用.
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