Relations between the changes of blood calcium, phosphorus, parathyroid hormone and bone mineral density and Child-Pugh classification among cirrhotic patients
Author(s): An Jihong, Wang Yong
Pages: 107-108,128
Year: 2007 Issue: 2
Journal: INFECTIOUS DISEASE INFORMATION
Keyword: 肝硬化; 血清钙; 甲状旁腺素; 骨密度; Child-Pugh分级;
Abstract: 目的 探讨肝硬化患者血清钙、磷、甲状旁腺素及骨密度指标的变化与Child-Pugh分级的关系.方法 肝硬化患者43例,Child-Pugh分级A级12例,B级16例,C级15例.正常对照组15例,男10例,女5例.用免疫放射法(IRMA)测定甲状旁腺素(PTH),生化检测血清钙(Ca2+)、磷(P3+),单光子骨矿分析仪检测尺骨平均密度.结果 血清甲状旁腺素随病情加重显著升高(P＜0.01);血清钙、尺骨平均骨密度随病情加重显著降低(P＜0.01);Child-Pugh分级A级患者血清甲状旁腺素、钙及骨密度和正常对照组检测结果比较,差异无统计学意义.结论 肝硬化患者血清钙、甲状旁腺素及骨密度的变化与肝性骨营养不良之间有密切关系,且与肝硬化程度密切相关.
Pages: 107-108,128
Year: 2007 Issue: 2
Journal: INFECTIOUS DISEASE INFORMATION
Keyword: 肝硬化; 血清钙; 甲状旁腺素; 骨密度; Child-Pugh分级;
Abstract: 目的 探讨肝硬化患者血清钙、磷、甲状旁腺素及骨密度指标的变化与Child-Pugh分级的关系.方法 肝硬化患者43例,Child-Pugh分级A级12例,B级16例,C级15例.正常对照组15例,男10例,女5例.用免疫放射法(IRMA)测定甲状旁腺素(PTH),生化检测血清钙(Ca2+)、磷(P3+),单光子骨矿分析仪检测尺骨平均密度.结果 血清甲状旁腺素随病情加重显著升高(P＜0.01);血清钙、尺骨平均骨密度随病情加重显著降低(P＜0.01);Child-Pugh分级A级患者血清甲状旁腺素、钙及骨密度和正常对照组检测结果比较,差异无统计学意义.结论 肝硬化患者血清钙、甲状旁腺素及骨密度的变化与肝性骨营养不良之间有密切关系,且与肝硬化程度密切相关.
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