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wei ai huan zhe wai zhou xue cd4+cd25+ diao jie xing t xi bao de bian hua
Author(s): 
Pages: 2675-2676
Year: Issue:  17
Journal: THE JOURNAL OF PRACTICAL MEDICINE

Keyword:  胃肿瘤调节性T细胞流式细胞仪;
Abstract: 目的:探讨胃癌患者外周血CD4+CD25+调节性T细胞的变化及临床意义.方法:应用流式细胞仪检测52例胃癌患者(胃癌组)和24例健康对照者(健康组)的CD4+CD25+调节性T细胞水平.结果:胃癌组外周血CD4+CD25+调节性T细胞较健康组明显升高,胃癌Ⅲ+Ⅳ期患者外周血CD4+CD25+调节性T细胞水平比Ⅰ+Ⅱ患者明显升高.结论:胃癌患者外周血CD4+CD25+调节性T细胞水平明显升高,可能是机体免疫功能受抑制的重要机制,并可成为胃癌患者机体免疫状态临床监测的指标.
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