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xue qing chao min c fan ying dan bai he bai jie su -6 zai nao geng si huan zhe zhong de ying yong
Author(s): 
Pages: 317-318
Year: Issue:  4
Journal: JIANGXI JOURNAL OF MEDICAL LABORATORY SCIENCES

Keyword:  超敏C反应蛋白白介素-6脑梗死;
Abstract: 目的 探讨脑梗死(CI)患者血清超敏C反应蛋白(hsCRP)和白介素-6(IL-6)水平的变化,及其与脑梗死严重程度的关系.方法 检测86例脑梗死患者血清hsCRP和IL-6水平,并分析其与脑梗死患者神经功能损伤程度的相关性.选取60例健康体检者作为对照.采用免疫比浊法检测hsCRP,用ELISA双抗体夹心法测IL-6.结果 脑梗死患者血清hsCRP浓度为15.48±2.87 mg/l,IL-6水平为20.23±4.86 ng/l,明显高于对照组(P<0.01).健康对照组hsCRP为2.48±0.52 mg/l,IL-6水平为8.56±2.38 ng/l.血清hsCRP和IL-6水平与脑梗死患者神经功能损伤程度呈正相关(P<0.01),重型患者明显高于轻、中型患者,差异均有显著意义.结论 脑梗死患者血清hsCRP和IL-6明显升高,而且与患者神经功能损伤程度呈正相关.hsCRP和IL-6水平升高为脑梗死患者发病的两个危险因素.
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