Author(s): QIU Shu, WANG Xue-bao, SUN Jie, ZHENG Xiao-mei, NI Liang
Pages: 39-42
Year: 2007 Issue:  7
Journal: CHEMISTRY & BIOENGINEERING
Keyword:  壳聚糖; 琼胶; 复合微球; 药物释放;
Abstract: 采用小分子离子交联法制备了pH值敏感的壳聚糖-琼胶复合微球,对壳聚糖-琼胶复合微球的粒径、形貌、pH值敏感性等进行了表征.以茶碱为模型药物研究了壳聚糖-琼胶复合微球的药物释放性能,结果发现一定量琼胶的引入有助于改善壳聚糖微球的药物缓释性能.