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Observation on Anti -proliferation and Apoptosis Inducement of Cells of Lung Cancer from Inonotus obliquus
Author(s): 
Pages: 40-43
Year: Issue:  4
Journal: EDIBLE FUNGI OF CHINA

Keyword:  桦褐孔菌肺肿瘤细胞凋亡细胞增殖;
Abstract: 用MTT法测定桦褐孔菌抗突变活性成分Inotodiol,对人肺癌A549细胞株的增殖抑制作用,20mg·L-1~80mg·L-1桦褐孔菌的抗突变活性成分Inotodiol对人肺癌A549细胞株有抑制增殖作用,且表现出浓度和时间依赖关系.在倒置显微镜下、HE染色光学显微镜下、AO/EB双染色荧光显微镜下、透射电子显微镜下观察,肿瘤细胞均有体积变小、有凋亡小体.桦褐孔菌的抗突变活性成分Inotodiol可抑制人肺癌A549细胞株的增殖和诱导肿瘤细胞凋亡.
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