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fen mian fang shi dui hbv mu ying zu duan xiao guo de ying xiang
Author(s): 
Pages: 29-29
Year: Issue:  6
Journal: CHINA MEDICAL HERALD

Keyword:  分娩方式HBV感染母婴传播;
Abstract: 目的:比较不同分娩方式对主被动联合免疫阻断乙型肝炎病毒(HBV)母婴传播效果的影响.方法:随机选取45例阴道分娩的HBsAg阳性孕妇为顺产组及45例择期剖宫产的HBsAg阳性孕妇为剖宫产组,所有新生儿生后2 h内抽取股静脉血送检乙肝六项及乙肝病毒DNA定量,24 h内注射乙肝免疫球蛋白(HBIg)200 U、乙肝疫苗20 μg(CHO细胞),生后1周时再次采血进行乙肝病毒DNA定量,比较两组结果.结果:两组在乙肝二对半血清标志物构成上无显著性差异;两组新生儿血中乙肝DNA拷贝数比较,阴道分娩组明显高于剖宫分娩组,有显著性差异.结论:分娩方式对主被动联合免疫阻断HBV母婴传播的效果无明显影响,在使用主被动联合免疫的情况下,剖宫产不能进一步降低母婴传播阻断失败的比例.
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