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luo ding xin dui yuan fa xing gao xue ya huan zhe yan zheng xiang guan dan bai de ying xiang
Author(s): 
Pages: 114-115
Year: Issue:  6
Journal: CHINA MEDICAL HERALD

Keyword:  高血压C反应蛋白白细胞介素6一氧化氮;
Abstract: 目的:探讨原发性高血压患者控制血压后炎症相关蛋白的表达水平及与正常人之间的差异.方法:采用免疫浊度法、放射免疫分析法、硝酸还原化学比色法测定41例已接受洛丁新降压治疗的高血压患者及50例正常人循环中C反应蛋白(CRP)、白细胞介素-6(IL-6)、一氧化氮(NO)等炎症相关蛋白的表达水平.结果:原发性高血压患者治疗前CRP、IL-6浓度高于正常对照组(P<0.01),NO浓度低于正常对照组(P<0.01);原发性高血压患者治疗后CRP、IL-6浓度低于治疗前浓度(P<0.05),NO浓度高于治疗前(P<0.05).结论:经洛丁新控制血压后,高血压患者炎症相关蛋白的表达水平下降.
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