The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Significance of C4d deposition in the follicular lymphoma
Author(s): 
Pages: 227-229
Year: Issue:  4
Journal: CHINESE JOURNAL OF HEMATOLOGY

Keyword:  抗原C4d淋巴瘤滤泡性;
Abstract: 目的 探讨滤泡性淋巴瘤(follicular lymphoma,FL)中C4d抗原的沉积及其意义.方法 对133份淋巴瘤标本进行C4d抗体的免疫组化染色,同时对FL进行CD35/C4d、CD21/C4d和Bcl-2/C4d抗体免疫组化双染色,观察C4d抗原沉积分布区域及阳性率.结果 26例FL中有19例肿瘤组织的瘤性滤泡中出现不规则网线状C4d抗原沉积;CD35/C4d、CD21/C4d和Bcl-2/C4d双染色证实,C4d抗原沉积在瘤性滤泡的滤泡树突细胞(follicular dendritic cell,FDC)周围;C4d阳性率与FL分级无关.FL弥漫区域以及其他类型淋巴瘤的肿瘤细胞间无C4d抗原沉积.结论 C4d抗原沉积在FL瘤性滤泡的FDC周围,是FL与其他类型淋巴瘤鉴别的较特异标志之一.
Related Articles
No related articles found