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Experimental Study on the Anti-Myocardial Ischemia Effect of Guanxinshu patch
Author(s): ZHANG Ying, SUN Cao
Pages: 230-
231
Year: 2007
Issue:
3
Journal: HEILONGJIANG MEDICINE JOURNAL
Keyword: 冠心舒贴:贴剂; 抗心肌缺血; 药理学实验;
Abstract: 目的:探讨冠心舒贴抗心肌缺血的药理作用.方法:对大鼠采用舌下静脉注射脑垂体后叶素,使动物产生急性心肌缺血模型,以心电图ST及T波产生的变化为指标,观察给药后的对抗作用,以验证冠心舒贴的临床疗效.结果:与生理盐水组比较,冠心舒贴高、低剂量组虽然不能明显对抗垂体后叶素所致大鼠T波的增值(P>0.05),但有降低T波增值趋势,且冠心舒贴同剂量组能有效提高心肌缺血阴性率(P<0.05).结论:冠心舒贴对大鼠急性心肌缺血有保护作用.
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