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Abnormal changes of C-reactive protein and troponin Ⅰ in congestive heart failure
Author(s): 
Pages: 145-147
Year: Issue:  2
Journal: CHINESE JOURNAL OF CARDIOVASCULAR REHABILITATION MEDICINE

Keyword:  心力衰竭充血性C反应蛋白质肌钙蛋白Ⅰ;
Abstract: 目的:探讨充血性心力衰竭(Congestive heart failure,CHF)时血清C反应蛋白(CRP)和肌钙蛋白Ⅰ(troponinⅠ,cTnl)异常的变化及其意义.方法:收集CHF患者60例.其中心功能Ⅱ级、Ⅲ级、Ⅳ级各20例.同时选取30例健康人作为对照组.以化学免疫荧光法定量测定血清CRP及cTnI水平.结果:CHF患者血CRP和cTnI水平明显高于对照组(P<0.01),心衰越重,其水平增高越明显;不同程度CHF患者,其组间差异性显著,呈正相关(P<0.01,r=0.735).CHF纠正后,血CRP和cTnI水平明显下降(P<0.01).结论:CHF患者血CRP和cTnI变化与CHF严重程度密切相关;而且CRP和cTnI水平呈正相关.
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