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Issue:
Involvement of Smad mediated signal pathway inkidney fibrosis
Author(s):
QIN Yanping
,
WANG Meimei
Pages:
84
-
88
Year:
2007
Issue:
1
Journal:
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
Keyword:
肾疾病
;
纤维变性
;
蛋白质类
;
信号传递
;
Abstract:
Smad蛋白是TGF-β超家族的下游信号传导蛋白,近年来许多研究结果表明TGF-β超家族在肾脏的促/抗纤维化效应主要是通过激活其细胞内信号传导蛋白Smad家族来实现的.本文拟对Smad信号通路在肾脏纤维化发生、发展中的作用作一综述.
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