Study of Serum Resistin Level in Patients with Obstructive Sleep Apnea Syndrome
Author(s): WANG Mei, ZHENG Ming-xiu
Pages: 40-42
Year: 2007 Issue: 1
Journal: JOURNAL OF KUNMING MEDICAL COLLEGE
Keyword: 阻塞性睡眠呼吸暂停综合征; 抵抗素; 研究;
Abstract: 目的 了解正常人、阻塞性睡眠呼吸暂停综合征(OSAS)患者血清抵抗素水平,探讨其与空腹血糖、体重指数的相关性.方法 所有受试对象精确测量身高、体重,计算体重指数(BMI).同步检测空腹血糖(FPG)、总胆固醇(Tc)、甘油三脂(TG),采用酶联免疫吸附试验(ELISA)检测空腹血清抵抗素浓度.OSAS患者组经多导睡眠检测仪测定其睡眠呼吸暂停通气指数(AHI)及最低血氧饱和度(SaO2).两组间比较用t检验,用Spearman和Pearson法进行相关分析.结果 (1)OSAS患者组血清抵抗素、BMI、TG比正常对照组高,且差异有统计学意义(P＜0.05);(2)血清抵抗素与BMI、FPG、TC正相关;(3)OSAS患者组BMI与AHI正相关、与SaO2负相关.结论 OSAS患者血清抵抗素浓度升高;空腹血清抵抗素浓度与体重指数、空腹血糖、血清总胆固醇正相关,表明抵抗素在OSAS患者的脂、糖代谢中起一定作用.
Pages: 40-42
Year: 2007 Issue: 1
Journal: JOURNAL OF KUNMING MEDICAL COLLEGE
Keyword: 阻塞性睡眠呼吸暂停综合征; 抵抗素; 研究;
Abstract: 目的 了解正常人、阻塞性睡眠呼吸暂停综合征(OSAS)患者血清抵抗素水平,探讨其与空腹血糖、体重指数的相关性.方法 所有受试对象精确测量身高、体重,计算体重指数(BMI).同步检测空腹血糖(FPG)、总胆固醇(Tc)、甘油三脂(TG),采用酶联免疫吸附试验(ELISA)检测空腹血清抵抗素浓度.OSAS患者组经多导睡眠检测仪测定其睡眠呼吸暂停通气指数(AHI)及最低血氧饱和度(SaO2).两组间比较用t检验,用Spearman和Pearson法进行相关分析.结果 (1)OSAS患者组血清抵抗素、BMI、TG比正常对照组高,且差异有统计学意义(P＜0.05);(2)血清抵抗素与BMI、FPG、TC正相关;(3)OSAS患者组BMI与AHI正相关、与SaO2负相关.结论 OSAS患者血清抵抗素浓度升高;空腹血清抵抗素浓度与体重指数、空腹血糖、血清总胆固醇正相关,表明抵抗素在OSAS患者的脂、糖代谢中起一定作用.
Citations
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