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Study on alteration of IL-2, sIL-2R in patients with chronic obstructive pulmonary disease
Author(s): 
Pages: 25-26
Year: Issue:  1
Journal: CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY

Keyword:  肺疾病慢性阻塞性白细胞介素-2受体白细胞介素-2;
Abstract: 目的 研究慢性阻塞性肺疾病(COPD)患者外周血中白细胞介素2(IL-2)、可溶性白细胞介素2受体(sIL-2R)的表达规律,探讨其相互关系及临床意义.方法 采用酶联免疫吸附法(ELISA)测定外周血IL-2、sIL-2R的含量.结果 COPD组IL-2含量为(65.66±12.98)pg/ml,与健康对照组(128.15±17.12)pg/ml相比明显降低(P<0.01),sIL-2R含量为(98.61±14.12)pg/ml,与健康对照组(91.01±9.98)pg/ml相比则明显升高(P<0.05).结论 COPD患者免疫功能低下.检测患者IL-2、sIL-2R含量在COPD的发生、发展、治疗、转归及预后方面具有重要的临床指导意义.
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