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The immunohistochemical expression of P-selectin in the healing process of incised skin wounds of rats
Author(s): 
Pages: 1462-1464
Year: Issue:  12
Journal: CHINESE JOURNAL OF LABORATORY DIAGNOSIS

Keyword:  皮肤创伤免疫组化P选择素;
Abstract: 目的 探讨P选择素的表达变化与损伤时间的关系.方法 应用免疫组织化学技术,对实验大鼠不同损伤时间的生前伤(5 min-7 d)皮肤组织中P选择素的表达变化进行观察,以大鼠死后伤组作为对照组.结果 在生前损伤组,最早至伤后10 min,P选择素即在血管内皮呈阳性表达,持续至伤后7 h,且P选择素随损伤时间变化呈规律性表达.在死后伤组未见上述改变.结论 P选择素可作为法医学皮肤损伤时间判定的有效指标.
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