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jia ti sha xing dui man xing zu sai xing fei ji bing huan zhe cha jian huan shi pian ti nei qing chu lv de ying xiang
Author(s): 
Pages: 687-689
Year: Issue:  11
Journal: WORLD CLINICAL DRUGS

Keyword:  加替沙星茶碱药物动力学;
Abstract: 目的 研究加替沙星对慢性阻塞性肺疾病(COPD)患者茶碱缓释片体内清除率的影响.方法 通过对临床慢性COPD患者联用加替沙星前后茶碱血药浓度的测定,获得相关药动学参数并作统计处理.结果 联用加替沙星前后茶碱血药浓度升高,清除率有显著降低.结论 加替沙星明显延缓茶碱在体内的代谢,临床上二者联用时应监测茶碱的血药浓度,以保证安全.
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