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Issue:
Investigation on Bovine Leukocyte Adhesion Deficiency
Author(s):
MA Jin-Zhu
,
CUI Yu-Dong
,
ZHU Zhan-Bo
,
CAO Hong-Wei
,
PIAO Fan-Ze
Pages:
1233
-
1236
Year:
2006
Issue:
10
Journal:
HEREDITAS(BEIJING)
Keyword:
牛白细胞粘附缺陷病
;
RT-PCR
;
CD18
;
Abstract:
牛白细胞粘附缺陷病(BLAD)是一种常染色体单基因隐性遗传疾病, 病因为白细胞表面整合素CD18亚单位基因突变所致.为了解我国奶牛群中BLAD的携带和发生情况, 本研究采用RT-PCR扩增CD18基因片段后, 用TaqⅠ内切酶对扩增产物进行酶切的方法检测了1 000头1~6岁的奶牛, 结果有19头奶牛为BLAD携带牛, 即BLAD携带率为1.9%;1头为BLAD病牛.
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