The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Pathological diagnosis of Paget's disease
Author(s): 
Pages: 511-513
Year: Issue:  7
Journal: ANHUI MEDICAL AND PHARMACEUTICAL JOURNAL

Keyword:  Paget病表皮原发腺癌Muc-1GCDFP-15病理诊断;
Abstract: 目的探讨乳腺Paget病(memmary paget's disease ,MPD)和乳腺外Paget病(extramammary paget's disease ,EMPD)的临床病理特征及其诊断.方法对61例Paget病(Paget's disease, PD)进行形态学观察、AB/PAS组化染色及免疫组化检测.结果① EMPD细胞具有独特的排列方式和细胞形态,MPD细胞形态与伴发的BC细胞类似.② GCDFP-15、Muc-1及CK8在MPD中的阳性表达率分别为2%(1/50)、92%(46/50)及88%(44/50),在EMPD中的阳性表达率分别为18%(2/11)、36%(4/11)及81%(9/11). 结论 PD是表皮内的腺癌,可分为原发与继发两类,原发性PD细胞可分为大汗腺样、皮脂腺样、黏液型及混合细胞型,诊断应排除病变周围原发性腺癌的存在;继发性PD大多来自深部相关肿瘤.
Related Articles
No related articles found