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Observation of curative effect of topiramate in treatment for convulsive status in children
Author(s): 
Pages: 1097-1099
Year: Issue:  6
Journal: JOURNAL OF JILIN UNIVERSITY(MEDICINE EDITION)

Keyword:  抗惊厥药惊厥/药物疗法儿童;
Abstract: 目的:探讨托吡酯治疗小儿惊厥持续状态的效果,寻找一种疗效确切且副作用小的治疗小儿惊厥持续状态的药物.方法:采取抽签法将小儿惊厥患儿随机分为托吡酯组(17例)和苯巴比妥组(16例),分别于治疗后24、48和72h判定2组的治疗效果.结果:托吡酯治疗惊厥持续状态在治疗后24、48和72h有效率分别为64.7%、76.5%和82.4%,苯巴比妥组有效率为68.8%、75.0%和75.0%.两组疗效比较差异无显著性(P>0.05).结论:托吡酯治疗惊厥持续状态与苯巴比妥负荷量法相比效果相似但副作用较少,可用于小儿惊厥持续状态的治疗.
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